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0224/2024 - Environmental and occupational parental exposure to pesticides and childhood cancer: a systematic review
Exposição parental ambiental e ocupacional aos agrotóxicos e câncer infanto-juvenil: uma revisão sistemática

Author:

• Mariana Rosa Soares - Soares, M. R. - <enf.marianasoares@gmail.com>
ORCID: https://orcid.org/0000-0002-0417-2614

Co-author(s):

• Pablo Cardozo Rocon - Rocon, P. C. - <pablocardoz@gmail.com>
ORCID: https://orcid.org/0000-0003-2696-5786
• Amanda Cristina de Souza Andrade - Andrade, A.C.S. - <csouza.amanda@gmail.com>
ORCID: https://orcid.org/0000-0002-3366-4423
• Wanderlei Antonio Pignati - Pignati, W. A. - <pignatimt@gmail.com>
ORCID: https://orcid.org/0000-0001-9178-6843


Abstract:

Objective: To describe and summarize the effects and characteristics of parental environmental and occupational exposure to pesticides on the development of childhood cancer (CIJ). Methods: A systematic literature review (RSL) was conduct in the VHL, MEDLINE, Pubmed, SciELO, Lilacs and BDENF databases, based on a question formulated based on the PICOS strategy and the recommendations of the Prisma declaration. Cohort and case-control studies that investigated the association between parental exposure and CIJ were included. The findings were systematized by themes and thematic categories. Results: 116 articles were found, of which 20 articles were included based on the RSL criteria. Environmental parental exposure to pesticides in homes was more frequently. The main occupational exposure was agricultural work. Exposure occurred in the pre-conception period, pregnancy or early childhood, mainly by pesticidesthe chemical group’s herbicides and organophosphate insecticides. Overall: Of the 20 articles included, only 2 did not identify any association. The others indicate an association or increased chance of CIJ in parental and environmental occupational exposure to pesticides, mainly on the development of leukemia.

Keywords:

parental exposure, environmental exposure, pesticides, childhood cancer, systematic review.

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Soares, M. R., Rocon, P. C., Andrade, A.C.S., Pignati, W. A.. Environmental and occupational parental exposure to pesticides and childhood cancer: a systematic review. Cien Saude Colet [periódico na internet] (2024/May). [Citado em 05/12/2025]. Está disponível em: http://www.cienciaesaudecoletiva.com.br/en/articles/environmental-and-occupational-parental-exposure-to-pesticides-and-childhood-cancer-a-systematic-review/19272



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